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Binge Drinking: Increased Dementia

Thursday, May 14th, 2009 Binge Drinking: Increased Dementia

It has been argued that more of the under 65 age group and more specifically women may suffer alcohol related brain damage according to the Observers Dennis Campbell, health correspondent (10 05 09).

Essentially, heavy drinking it has been suggested may be to blame for as many as one in four cases of dementia.

It is understood that doctors that doctors have associated alcohol intake to the development of the brain-wasting condition in as many as 10 and 24% of the estimated 700,000 people in the UK with the disease. Such are their concerns that they are warning that both binge drinking and increased intake are more than likely to lead to an epidemic of alcohol related brain damage. They conclude that drinkers could experience very serious memory issues in their forties.

Notwithstanding, it has also been established that women who drink a lot more are at greater risk from the condition than men because of they are physiologically less well able to cope with alcohol’s effects. Nevertheless, alcohol is known to kill brain cells. However, the estimate of its impact on neurological health, contained in the journal Alcohol and Alcoholism indicates that the problem may be much more widespread than previously thought.

More importantly the authors of the report argue that the increase in the amount that people drink suggests that “it is therefore likely that prevalence rates of alcohol-related brain damage are currently underestimated and may rise in future generations”.

Hitherto one of the co-authors and consultant psychiatrist at the Maudsley Hospital in south London, Jane Marshall says, “People think that dementia is something that happens to people over 65. But a lot of those under 65 have got cognitive problems and a large proportion of the problems in that group are related to alcohol. Alcohol-related brain damage may account for 10-24% of all cases of all forms of dementia. We know that alcohol is associated with serious cognitive impairment. It reduces memory and general cognition,”

The conclusions found from American research last year suggest that consuming more than two drinks a day can bring forward the onset of Alzheimer’s by as much as 4.8 years. Two thirds of all the 700,000 people in the UK with dementia have Alzheimer’s.

“Drink is more likely to help induce dementia in women than men because women have more body water and less body fat, which means that they metabolise alcohol differently and so are more vulnerable,” said Marshall.

Women who drink the same as men have a higher risk of cognitive impairment for that reason, in the same way that they are at higher risk of getting alcohol-related liver disease.

What also requires some consideration is the fact that both male and female heavy drinkers who abstain from alcohol can expect to see brain cells regenerate and improvements in key areas of brain activity, thus it is all not bad news.

The Alzheimer’s Societies Gayle Willis states, “We know that the prolonged use of alcohol can lead to memory deficiencies. Only one third of the people with Alzheimer’s are diagnosed, but the problem of under-diagnosis of people with alcohol-related memory impairment could be even greater.” But the society believes that only a handful of all cases of dementia, perhaps as few as 3%, are directly attributable to alcohol.

Marshall and her colleagues examined Korsakoff’s syndrome, a little-known form of dementia linked to alcohol intake, characterised by short-term memory loss, changes in behaviour and confusion. It is increasingly common in Scotland and the Netherlands, especially among poorer people with poor diets. One study of sufferers found that half were under 50.

Professor Ian Gilmore, president of the Royal College of Physicians, said: “It is really concerning that awareness among clinical staff of this important link between alcohol and dementia remains poor, yet detection of early signs often gives a real chance of successfully heading off the condition. It is vital that we improve understanding among doctors and nurses about the links between heavy drinkers and neurological damage. Equally important is that people understand that alcohol-related brain damage can strike at any time of life.”

In contrast, other research has indicated that moderate drinking which represents two drinks per day can actually protect against the onset of the disorder.

Finally, Dr Allan Thomson, the guest editor of Alcohol and Alcoholism and spokesman for the Medical Council on Alcohol, has written to Dawn Primarolo, the public health minister, warning that the NHS must give alcohol-related brain damage the same priority it has put into liver problems linked to heavy drinking.

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